Surgical robots, early cancer tests top CB Insights digital health startup list

Dive Brief: The 150 digital health startups deemed the most promising by market intelligence firm […]

Dive Brief:

  • The 150 digital health startups deemed the most promising by market intelligence firm CB Insights have raised more than $20 billion in total funding across over 600 deals from more than 900 investors, according to annual rankings released Thursday.
  • U.K. surgical robotics company CMR Surgical made the list of 12 “unicorns,” or companies valued at more than $1 billion. Smaller robotic surgery player Vicarious Surgical, which pairs miniaturized robotics with virtual reality and won a breakthrough device designation from FDA late last year, was included in the broader list of 150.
  • Twenty-four companies featured this year, or 16% of the list, focus on screening and diagnostics, including direct-to-consumer testing, medical imaging and digital pathology. Those companies include early cancer detection startups such as Freenome, Grail and Thrive Earlier Detection, as well as AI-supported imaging platform makers Subtle Medical, Zebra Medical Imaging, and Viz.ai, which has partnered with Medtronic.

Dive Insight:

CB Insights researchers looked at nearly 8,000 digital health startups for the yearly analysis, choosing 150 of what they deem most promising companies based on factors such as patent activity, competitive landscape and tech novelty. Startups based in the U.S. dominated this year’s list, accounting for 77% of the companies from 18 different countries. Medtech selections also came from Israel, the U.K., China, South Korea and India, to name a few.
Digital therapeutics makers Pear TherapeuticsAkili Interactive Labs, Kaia Health and Happify Health all made the list of 150. The group of nine companies classified in the medical devices and equipment category included diabetes management device developer Bigfoot Biomedical, as well as fertility and pregnancy testing and remote monitoring tech providers Modern Fertility and Nuvo.

Medical device, equipment, and screening & diagnostics startups included in the 2020 CB Insights list
Company Offering Total disclosed funding Select investors
Bigfoot Biomedical Insulin delivery $163M Cormorant Asset Mgmt., Janus Henderson Investors, JDRF T1D Fund, Quadrant Capital Adv., Senvest Cap.
Caption Health AI-assisted ultrasound acquisition $70M Khosla Ventures, Data Collective, Atlantic Bridge Cap., 11.2 Capital, National Science Foundation
ChromaCode Signal processing to improve molecular testing $52M New Enterprise Associates, Domain Associates, Northpond Ventures, Windham Venture Partners, Okapi Venture Cap.
CMR Surgical Robotic surgery $386M Cambridge Innovation Cap., Escala Cap., LGT Cap. Partners, Watrium, ABB Tech. Ventures
Cue Health Portable testing $166M Johnson & Johnson Innovation, Foresite Cap., Decheng Cap., Section 32, Madrone Cap. Partners
Element Science Patch-based wearable cardioverter defibrillator $193M Google Ventures, Qiming Venture Partners, Third Rock Ventures, Invus Group, Deerfield Mgmt.
Freenome Early cancer detection $239M Andreessen Horowitz, T. Rowe Price, Google Ventures, Founders Fund, Data Collective
Grail Early cancer detection $2.005B ARCH Venture Partners, Tencent Holdings, Kleiner Perkins Caufield & Byers, Hillhouse Cap. Mgmt., Sequoia Cap. China
Healthy.io Smartphone urinalysis $78M JOY Cap., Samsung NEXT, Aleph, Corner Ventures, Ansonia Holdings Singapore
icometrix Imaging AI for neurological disorders $20M Optum Ventures, Capricorn Partners, Forestay Cap., KU Leuven
Infervision AI to help diagnose cancer $73M Sequoia Cap. China, Qiming Venture Partners, Genesis Cap., Xiang He Cap., CDH Investments
Karius NGS tests for infectious disease $240M SoftBank Group, Lightspeed Venture Partners, Tencent Holdings, Khosla Ventures, General Catalyst
LetsGetChecked DTC diagnostic testing kits $113M Qiming Venture Partners, Deerfield Mgmt., Optum Ventures,  Illumina Ventures, Transformation Cap.
Lunit Developing novel imaging biomarkers $49M NH Investment & Securities, Legend Cap., Softbank Ventures Asia, FUJIFILM Holdings Corporation, InterVest
Mammoth Biosciences CRISPR tech for diagnostic testing $89M Mayfield Fund, 8VC, Decheng Cap., NFX, National Institutes of Health
Modern Fertility At-home fertility hormone test $22M Y Combinator, Union Square Ventures, SV Angel, Forerunner Ventures, First Round Cap.
Nuvo Remote monitoring for pregnancy $43M Shareholder Value Mgmt.
Onera Sleep diagnostics $13M BOM Brabant Ventures, imec.xpand, EIC Accelerator, Eurostars Programme
Paige.AI Digital pathology $95M Goldman Sachs, Breyer Cap., Memorial Sloan Kettering Cancer Center, Kenan Turnacioglu, HealthCare Ventures
PathAI Evolving pathology for disease diagnosis $90M General Catalyst, General Atlantic, 8VC, Refactor Cap., Pillar
Perspectum Digital technologies to help treat liver disease $36M The Blue Venture Fund, Oxford Sciences Innovation, University of Oxford, HealthQuest Cap., Puhua Cap.
Qure.ai AI to interpret radiological images $16M Sequoia Cap. India, MassMutual Ventures
Subtle Medical Deep learning-enhanced medical imaging $8M Bessemer Venture Partners, Data Collective, Baidu Ventures, ZhenFund
Thrive Earlier Detection Early cancer detection $367M T. Rowe Price, Invus Group, Casdin Capital, Bain Capital, Perceptive Advisors
Vicarious Surgical Surgical robotics and virtual reality $44M Khosla Ventures, AME Cloud Ventures, Innovation Endeavors, Marc Benioff, E15VC
Viz.ai AI to identify strokes $79M Google Ventures, Kleiner Perkins Caufield & Byers, Greenoaks Cap. Mgmt., Threshold Ventures, CRV
Winterlight Labs Speech-based cognitive assessment using AI $5M Grey Sky Venture Partners, Hikma Ventures, First Star Ventures, Pacific Health Ventures, Amplify Cap.
Zebra Medical Vision AI-assisted medical imaging $50M Khosla Ventures, OurCrowd, Johnson & Johnson Innovation, Dolby Family Ventures, Marc Benioff

Source: CB Insights

The coronavirus pandemic led to a rapid adoption of telehealth in particular, though other remote care players are stepping up with more specialized services.
Sixty-two startups, or 41% of the list, sell telehealth services, including platforms such as Doctor on Demand, Heartbeat Health and Livi. Remote monitoring and diagnostics platforms like Oura and Element Science and therapy and coaching apps like Omada Health and Virta Health also made the list.
Some startups are forming partnerships with key industry players, including Happify, whose digital therapeutics target mental health needs. It has partnerships with the American Heart Association, Sanofi and Cigna. Private health insurance startup Bright Health has partnered with Mount Sinai Health System and Mercy Health, according to the report.
Beyond telehealth, another leading category this year is clinical intelligence and enablement. CB Insights picked 26 of those companies, which make tools to help providers and payers make clinical decisions to deliver care more efficiently. These include platforms such as Twistle and Wellth, which connect patients and providers, and Quartet Health, which coordinates mental health care.
In the first quarter of 2020, mental health startups raised a record $575 million in equity funding, according to the report. Ten companies on this year’s list provide mental and behavioral health services, including teletherapy platforms like Lyra Health and Meru Health and addiction management platforms like Axial Healthcare and CureApp.
Seventeen of the 150 digital health companies on last year’s list have remained or since became unicorns, while two went public and two were acquired.
Original Article: (https://www.medtechdive.com/news/digital-health-companies-raise-20-billion-CB-insights/583489/)